- The final sample size consisted of 2,064 trios, 896 cases, and 2,455 controls. For each study, these investigators imputed HapMap single nucleotide polymorphisms, computed association test statistics and transformed them to z-scores, and then combined weighted z-scores in a meta-analysis. No genome-wide significant associations were found, although an analysis of candidate genes suggests that they may be involved in the disorder. The authors concluded that given that ADHD is a highly heritable disorder, theser negative results suggested that the effects of common ADHD risk variants must, individually, be very small or that other types of variants, e.g., rare ones, account for much of the disorders heritability.
Source : http://www.aetna.com/cpb/medical/data/400_499/0426.html
- Its unclear what causes these irregularities, but ADHD runs in families, so many experts believe genetics play a role.Like many other illnesses, ADHD probably results from a combination of genetic and environmental factors such as nutrition, brain injuries, or social environment. Types of ADHD in Children Combined Type (Inattentive/Hyperactive/Impulsive).
Source : http://prezi.com/sy6y85e_okt7/attention-deficit-hyperactivity-disorder/
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